Welcome to the Niu Group in the Department of Chemistry, Boston College. Taking inspirations from Nature, we build synthetic macromolecules and biopolymer analogs via synthetic chemistry, directed evolution, and synthetic biology, for pressing needs in materials and biomedical sciences.  

A group picture of the Niu Research Group

What we do

Sustainable polymers

We develop novel polymer chemistry for the synthesis of polymers that are built from bio renewable resources and can degrade upon triggered by external stimuli.


We develop glycomimetic macromolecules with defined structures and sequences and use them to probe the complex interactions between polysaccharides and their receptors.

Genome editing technologies

We develop non-nuclease CRISPR editors using protein engineering and directed evolution techniques for editing the DNA and RNA interactome.

We acknowledge the support from: